Refractory High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements

Preferred Label : Refractory High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements;

NCIt synonyms : Refractory High-Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements;

NCIt definition : High-grade B-cell lymphoma with MYC, BCL2, and BCL6 rearrangements that is resistant to treatment.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL970999;

Details

Origin ID

C162453;

UMLS CUI

C5206566;

Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Has cytogenetic abnormalities
- BCL2 Gene Rearrangement [NCIt concept]
- BCL6 Gene Rearrangement [NCIt concept]
- MYC Gene Rearrangement [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Large B-Lymphocyte [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Diffuse Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Refractory Disease [NCIt concept]
- Triple Hit Lymphoproliferative Lesion [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- BCL2 Gene [NCIt concept]
- BCL6 Gene [NCIt concept]
- MYC Gene [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]

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