GRAM Domain-Containing Protein 4

Preferred Label : GRAM Domain-Containing Protein 4;

NCIt synonyms : Death-Inducing Protein; Death-Inducing-Protein; GRAMD4;

NCIt definition : GRAM domain-containing protein 4 (578 aa, 66 kDa) is encoded by the human GRAMD4 gene. This protein is involved in the modulation of E2F1-induced apoptosis and the downregulation of toll-like receptor 9-dependent immune responses.;

Details

Origin ID

C205764;

OMIM relation
- Gram domain-containing protein 4 [OMIM gene]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- GRAMD4 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
- Mitochondrial Membrane [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Caspase Activation [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]

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