CASP8 and FADD-Like Apoptosis Regulator Isoform 2

Preferred Label : CASP8 and FADD-Like Apoptosis Regulator Isoform 2;

NCIt synonyms : FLIP-S; Cellular FLICE-Like Inhibitory Protein Isoform 2; CLARP2; cFLIPS; MRIT Beta-1; FLIPS; cFLIP(S); CFLAR Isoform 2; c-FLIPS; CASH Beta; Caspase Homolog Beta; Cellular FLICE-Like Inhibitory Protein Short Isoform; MACH-Related Inducer of Toxicity Beta-1; c-FLIP(S);

NCIt definition : CASP8 and FADD-like apoptosis regulator isoform 2 (221 aa, 25 kDa) is encoded by the human CFLAR gene. This protein is involved in the regulation of caspase-dependent apoptosis.;

Details

Origin ID

C112064;

UMLS CUI

C1308278;

Automatic exact mappings (from CISMeF team)
- CASP8 and FADD-Like apoptosis regulating protein [MeSH Descriptor]
- Casp8- and fadd-like apoptosis regulator [OMIM gene]
- fluorescence recovery after photobleaching [MeSH Descriptor]
OMIM relation
- Casp8- and fadd-like apoptosis regulator [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CFLAR protein, human [MeSH Supplementary Concept]
- CFLAR protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- CFLAR Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Death Domain [NCIt concept]
gene_product_is_element_in_pathway
- FAS Signaling Pathway PID [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Caspase-Dependent Apoptosis [NCIt concept]

Keyword's position in hierarchy(ies) :

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