CASP8 and FADD-Like apoptosis regulating protein

Preferred Label : CASP8 and FADD-Like apoptosis regulating protein;

MeSH definition : An APOPTOSIS-regulating protein that is structurally related to CASPASE 8 and competes with CASPASE 8 for binding to FAS ASSOCIATED DEATH DOMAIN PROTEIN. Two forms of CASP8 and FADD-like apoptosis regulating protein exist, a long form containing a caspase-like enzymatically inactive domain and a short form which lacks the caspase-like domain.;

MeSH synonym : flice-inhibitory protein; flip (cellular); casper protein; flice inhibitory protein; CASP8 and FADD like apoptosis regulating protein;

MeSH hyponym : FLICE-Inhibitory protein short form; FLICE-Inhibitory protein long form; FLICE Inhibitory Protein Short Form; FLIP-S Protein; FLIP S Protein; FLIP-S; FLICE Inhibitory Protein Long Form; FLIP-L Protein; FLIP L Protein; FLIP-L;

Is substance : O;

Details

Origin ID

D053446;

UMLS CUI

C0540654;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CASP8 and FADD-Like Apoptosis Regulator [NCIt concept]
- CASP8 and FADD-Like Apoptosis Regulator Isoform 2 [NCIt concept]
- CFLAR wt Allele [NCIt concept]
- Casp8- and fadd-like apoptosis regulator [OMIM gene]
- FLICE Inhibitory Protein [NCIt concept]
- Protein CASP [NCIt concept]
Record concept(s)
- CASP8 and FADD-Like apoptosis regulating protein [MeSH concept]
- FLICE-Inhibitory protein long form [MeSH concept]
- FLICE-Inhibitory protein short form [MeSH concept]
Related MeSH Supplementary Concept(s)
- CFLAR protein, human [MeSH Supplementary Concept]
- CFLAR protein, rat [MeSH Supplementary Concept]
- cflar protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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