CASP1 wt Allele

Preferred Label : CASP1 wt Allele;

NCIt synonyms : P45 Gene; IL1BC; Interleukin-1 Beta Converting Enzyme Gene; Caspase-1 Gene; IL1BCE; Interleukin 1-Beta Convertase Gene; IL-1BC; ICE; IL-1 Beta Converting Enzyme Gene; Caspase 1, Apoptosis-Related Cysteine Protease wt Allele; CASP-1; IL1B-Convertase Gene; Interleukin 1-B Converting Enzyme Gene;

NCIt definition : Human CASP1 wild-type allele is located within 11q23 and is approximately 76 kb in length. This allele, which encodes caspase-1 protein, is involved in the cleavage of IL-1 beta releasing the active form of this cytokine. Loss of CASP1 gene expression is associated with prostate cancer.;

GenBank Accession Number : NM_033292;

Details

Origin ID

C49549;

UMLS CUI

C1705786;

False automatic mappings
- Ice (substance) [SNOMED CT concept]
- Icing (substance) [SNOMED CT concept]
- ice [MeSH Descriptor]
- ice [SNOMED Notion]
- ice [MeSH concept]
OMIM relation
- Caspase 1, apoptosis-related cysteine protease [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 11: 104411067-104401445 [NCIt concept]
gene_in_chromosomal_location
- 11q23 [NCIt concept]
gene_is_element_in_pathway
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Caspase Cascade Pathway [NCIt concept]
- Caspase Cascade in Apoptosis [NCIt concept]
- Cellular Anthrax Toxin Pathway [NCIt concept]
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- D4-GDI Signaling Pathway [NCIt concept]
- IL18 Signaling Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Hydrolysis [NCIt concept]
- Inflammatory Response [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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