CASP2 wt Allele

Preferred Label : CASP2 wt Allele;

NCIt synonyms : ICH-1L; NEDD2 Apoptosis Regulatory Gene; ICH-1 Protease Gene; Caspase 2, Apoptosis-Related Cysteine Protease wt Allele; ICH1; ICH-1L/1S; CASP-2; Caspase-2 Gene; NEDD2; NEDD-2; PPP1R57; ICE and CED3 Homolog 1 Gene; Neural Precursor Cell Expressed, Developmentally Downregulated 2 Gene;

NCIt definition : Human CASP2 wild-type allele is located within 7q34-q35 and is approximately 19 kb in length. This allele, which encodes caspase-2 protein, plays a role in the activation of caspase-dependent apoptosis.;

GenBank Accession Number : NM_032984;

Details

Origin ID

C49552;

UMLS CUI

C1705061;

OMIM relation
- Caspase 2, apoptosis-related cysteine protease [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 7: 142502239-142521622 [NCIt concept]
gene_in_chromosomal_location
- 7q34-q35 [NCIt concept]
gene_is_element_in_pathway
- Caspase Cascade Pathway [NCIt concept]
- Caspase Cascade in Apoptosis [NCIt concept]
- HIV-1 Nef: Negative Effector Pathway for Fas and TNF-Alpha [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- TNFR1 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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