CD27 Antigen - CISMeF

Preferred Label : CD27 Antigen;

NCIt synonyms : Tumor Necrosis Factor Receptor Superfamily, Member 7; T-Cell Activation Antigen CD27; CD27 Molecule; T-Cell Activation Antigen S152; CD27L Receptor; Tumor Necrosis Factor Receptor Superfamily Member 7; TNFRSF7;

NCIt definition : CD27 antigen (260 aa, 29 kDa) is encoded by the human CD27 gene. This protein is involved in regulating B-cell activation, immunoglobulin synthesis, and apoptosis.;

Details

Origin ID

C104073;

UMLS CUI

C4721547;

Automatic exact mappings (from CISMeF team)
- CD27 Ag [LOINC component]
- CD27 Ligand [MeSH Descriptor]
- CD27 molecule [ORDO Gene]
- CD27 molecule [HGNC gene]
- Cd27 antigen [OMIM gene]
- Tumor Necrosis Factor Receptor Superfamily, Member 7 [MeSH Descriptor]
- Tumor Necrosis Factor Receptor Superfamily, Member 7 [MeSH concept]
OMIM relation
- Cd27 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CD27 Ag [LOINC component]
- Lymphocyte antigen CD27 (substance) [SNOMED CT concept]
- Tumor Necrosis Factor Receptor Superfamily, Member 7 [MeSH concept]
- Tumor Necrosis Factor Receptor Superfamily, Member 7 [MeSH Descriptor]
- lymphocyte antigen cd27 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD27 Gene [NCIt concept]
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Survival [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- Anti-CD27 Monoclonal Antibody GEN1053/BNT313 [NCIt concept]
- Anti-PD-L1/CD27 Bispecific Antibody CDX-527 [NCIt concept]
- Boserolimab [NCIt concept]
- Varlilumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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