Tumor Necrosis Factor Signaling Process

Preferred Label : Tumor Necrosis Factor Signaling Process;

NCIt synonyms : Tumor Necrosis Factor Activation;

NCIt definition : Any process which promotes expression of tumor necrosis factors, their subsequent secretion, binding to cognate receptors and intracellular signaling, and results in promoting insulin resistance, fever and macrophage phagocytosis, stimulating the hypothalmic-pituitary-adrenal axis and acute phase responses, and suppressing appetite. This process is involved in coordinating systemic responses to pathogenic infection.;

Details

Origin ID

C40589;

UMLS CUI

C1519684;

Semantic type(s)
- Physiologic Function [UMLS semantic type]
biological_process_involves_gene_product
- Adiponectin [NCIt concept]
- CD27 Antigen [NCIt concept]
- CD40 Ligand [NCIt concept]
- CD70 Antigen [NCIt concept]
- Caspase Recruitment Domain-Containing Protein 14 [NCIt concept]
- E3 Ubiquitin-Protein Ligase TRAIP [NCIt concept]
- EDA Gene Product [NCIt concept]
- Ectodysplasin-A1 [NCIt concept]
- Ectodysplasin-A2 [NCIt concept]
- Lymphotoxin-Alpha [NCIt concept]
- Lymphotoxin-Beta [NCIt concept]
- Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 [NCIt concept]
- Mixed Lineage Kinase Domain-Like Protein [NCIt concept]
- Sharpin [NCIt concept]
- Soluble Tumor Necrosis Factor Receptor Superfamily Member 1A [NCIt concept]
- Soluble Tumor Necrosis Factor Receptor Superfamily Member 8 [NCIt concept]
- Soluble Tumor Necrosis Factor Receptor Superfamily Member 9 [NCIt concept]
- TNF Receptor Family Protein [NCIt concept]
- TNFRSF1A Gene Product [NCIt concept]
- TNFRSF8 Gene Product [NCIt concept]
- TNFRSF9 Gene Product [NCIt concept]
- TRAF Family Member-Associated NF-Kappa-B Activator [NCIt concept]
- Tumor Necrosis Factor [NCIt concept]
- Tumor Necrosis Factor Family Protein [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 10 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 11 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 12 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 13 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 13B [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 14 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 15 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 18 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 4 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 6 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 8 [NCIt concept]
- Tumor Necrosis Factor Ligand Superfamily Member 9 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 10A [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 10B [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 10C [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 10D [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 11A [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 11B [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 12A [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 13B [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 13C [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 14 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 16 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 17 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 18 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 19 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 19L [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 1A [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 1B [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 21 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 25 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 27 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 3 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 4 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 5 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 6 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 6B [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 8 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member 9 [NCIt concept]
- Tumor Necrosis Factor Receptor Superfamily Member EDAR [NCIt concept]
process_involves_gene
- ADIPOQ Gene [NCIt concept]
- ADIPOQ wt Allele [NCIt concept]
- CARD14 Gene [NCIt concept]
- CARD14 wt Allele [NCIt concept]
- CD27 Gene [NCIt concept]
- CD27 wt Allele [NCIt concept]
- CD40 Gene [NCIt concept]
- CD40 wt Allele [NCIt concept]
- CD40LG Gene [NCIt concept]
- CD40LG wt Allele [NCIt concept]
- CD70 Gene [NCIt concept]
- CD70 wt Allele [NCIt concept]
- EDA Gene [NCIt concept]
- EDA wt Allele [NCIt concept]
- EDA2R Gene [NCIt concept]
- EDA2R wt Allele [NCIt concept]
- EDAR Gene [NCIt concept]
- EDAR wt Allele [NCIt concept]
- FAS Gene [NCIt concept]
- FAS wt Allele [NCIt concept]
- FASLG Gene [NCIt concept]
- FASLG wt Allele [NCIt concept]
- LTA Gene [NCIt concept]
- LTA wt Allele [NCIt concept]
- LTB Gene [NCIt concept]
- LTB wt Allele [NCIt concept]
- LTBR Gene [NCIt concept]
- LTBR wt Allele [NCIt concept]
- MAP4K3 Gene [NCIt concept]
- MAP4K3 wt Allele [NCIt concept]
- MLKL Gene [NCIt concept]
- MLKL wt Allele [NCIt concept]
- NGFR Gene [NCIt concept]
- NGFR wt Allele [NCIt concept]
- RELT Gene [NCIt concept]
- RELT wt Allele [NCIt concept]
- SHARPIN Gene [NCIt concept]
- SHARPIN wt Allele [NCIt concept]
- TANK Gene [NCIt concept]
- TANK wt Allele [NCIt concept]
- TNF Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNF wt Allele [NCIt concept]
- TNFRSF10A Gene [NCIt concept]
- TNFRSF10A wt Allele [NCIt concept]
- TNFRSF10B Gene [NCIt concept]
- TNFRSF10B wt Allele [NCIt concept]
- TNFRSF10C Gene [NCIt concept]
- TNFRSF10C wt Allele [NCIt concept]
- TNFRSF10D Gene [NCIt concept]
- TNFRSF10D wt Allele [NCIt concept]
- TNFRSF11A Gene [NCIt concept]
- TNFRSF11A wt Allele [NCIt concept]
- TNFRSF11B Gene [NCIt concept]
- TNFRSF11B wt Allele [NCIt concept]
- TNFRSF12A Gene [NCIt concept]
- TNFRSF12A wt Allele [NCIt concept]
- TNFRSF13B Gene [NCIt concept]
- TNFRSF13B wt Allele [NCIt concept]
- TNFRSF13C Gene [NCIt concept]
- TNFRSF13C wt Allele [NCIt concept]
- TNFRSF14 Gene [NCIt concept]
- TNFRSF14 wt Allele [NCIt concept]
- TNFRSF17 Gene [NCIt concept]
- TNFRSF17 wt Allele [NCIt concept]
- TNFRSF18 Gene [NCIt concept]
- TNFRSF18 wt Allele [NCIt concept]
- TNFRSF19 Gene [NCIt concept]
- TNFRSF19 wt Allele [NCIt concept]
- TNFRSF1A Gene [NCIt concept]
- TNFRSF1A wt Allele [NCIt concept]
- TNFRSF1B Gene [NCIt concept]
- TNFRSF1B wt Allele [NCIt concept]
- TNFRSF21 Gene [NCIt concept]
- TNFRSF21 wt Allele [NCIt concept]
- TNFRSF25 Gene [NCIt concept]
- TNFRSF25 wt Allele [NCIt concept]
- TNFRSF4 Gene [NCIt concept]
- TNFRSF4 wt Allele [NCIt concept]
- TNFRSF6B Gene [NCIt concept]
- TNFRSF6B wt Allele [NCIt concept]
- TNFRSF8 Gene [NCIt concept]
- TNFRSF8 wt Allele [NCIt concept]
- TNFRSF9 Gene [NCIt concept]
- TNFRSF9 wt Allele [NCIt concept]
- TNFSF10 Gene [NCIt concept]
- TNFSF10 wt Allele [NCIt concept]
- TNFSF11 Gene [NCIt concept]
- TNFSF11 wt Allele [NCIt concept]
- TNFSF12 Gene [NCIt concept]
- TNFSF12 wt Allele [NCIt concept]
- TNFSF13 Gene [NCIt concept]
- TNFSF13 wt Allele [NCIt concept]
- TNFSF13B Gene [NCIt concept]
- TNFSF13B wt Allele [NCIt concept]
- TNFSF14 Gene [NCIt concept]
- TNFSF14 wt Allele [NCIt concept]
- TNFSF15 Gene [NCIt concept]
- TNFSF15 wt Allele [NCIt concept]
- TNFSF18 Gene [NCIt concept]
- TNFSF18 wt Allele [NCIt concept]
- TNFSF4 Gene [NCIt concept]
- TNFSF4 wt Allele [NCIt concept]
- TNFSF8 Gene [NCIt concept]
- TNFSF8 wt Allele [NCIt concept]
- TNFSF9 Gene [NCIt concept]
- TNFSF9 wt Allele [NCIt concept]
- TRAIP Gene [NCIt concept]
- TRAIP wt Allele [NCIt concept]
- Tumor Necrosis Factor Family Gene [NCIt concept]

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