Tumor Necrosis Factor Receptor Superfamily Member 10C

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 10C;

NCIt synonyms : Antagonist Decoy Receptor For TRAIL/Apo-2L; TNF-Related Apoptosis-Inducing Ligand Receptor 3; TNFRSF10C; TRAIL-R3; CD263 Antigen; Decoy TRAIL Receptor Without Death Domain; Decoy Receptor 1; Lymphocyte Inhibitor of TRAIL; DcR1; TRAIL Receptor without an Intracellular Domain; TRAIL Receptor 3; CD263;

NCIt definition : Tumor necrosis factor receptor superfamily member 10C (259 aa, 27 kDa) is encoded by the human TNFRSF10C gene. This protein is involved in both binding to tumor necrosis factor ligand superfamily member 10 and the inhibition of apoptosis.;

NCIt note : Tumor necrosis factor receptor superfamily member 10C is a decoy receptor for tumor necrosis factor superfamily member 10 because it lacks a cytoplasmic death domain. Therefore, it does not induce apoptosis.;

Details

Origin ID

C104520;

UMLS CUI

C1621918;

Automatic exact mappings (from CISMeF team)
- Dicer 1, ribonuclease III [OMIM gene]
- Tumor necrosis factor receptor superfamily, member 10c [OMIM gene]
- receptors, tumor necrosis factor, member 10c [MeSH Descriptor]
OMIM relation
- Tumor necrosis factor receptor superfamily, member 10c [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TNFRSF10C protein, human [MeSH concept]
- TNFRSF10C protein, human [MeSH Supplementary Concept]
- receptors, tumor necrosis factor, member 10c [MeSH concept]
- receptors, tumor necrosis factor, member 10c [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF10C Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Inhibitor [NCIt concept]
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Apoptosis Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- TRAIL Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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