CD70 Antigen - CISMeF

Preferred Label : CD70 Antigen;

NCIt synonyms : Ki-24 Antigen; CD70 Molecule; CD27 Ligand; Surface Antigen CD70; Tumor Necrosis Factor (Ligand) Superfamily, Member 7; TNFSF7; CD27L; Tumor Necrosis Factor Ligand Superfamily Member 7;

NCIt definition : CD70 antigen (193 aa, 21 kDa) is encoded by the human CD70 gene. This protein is involved in T-cell activation and proliferation and may also play a role in B-cell activation.;

Details

Origin ID

C104079;

UMLS CUI

C1664176;

Automatic exact mappings (from CISMeF team)
- CD27 Ligand [MeSH Descriptor]
- CD27 Ligand [MeSH concept]
- CD70 molecule [ORDO Gene]
- CD70 molecule [HGNC gene]
- Cd70 antigen [OMIM gene]
OMIM relation
- Cd70 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CD27 Ligand [MeSH concept]
- CD27 Ligand [MeSH Descriptor]
- CD70 protein, human [MeSH concept]
- CD70 protein, human [MeSH Supplementary Concept]
- Lymphocyte antigen CD70 (substance) [SNOMED CT concept]
- lymphocyte antigen cd70 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD70 Gene [NCIt concept]
- Cytokine Gene [NCIt concept]
- Tumor Necrosis Factor Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Death Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Receptor Binding [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- Allogeneic Anti-CD70-CAR T-cells ALLO-316 [NCIt concept]
- Allogeneic Anti-CD70-CAR-IL-15-transduced Cord Blood-derived Natural Killer Cells [NCIt concept]
- Allogeneic CRISPR-Cas9 Engineered Anti-CD70 CAR-T Cells CTX130 [NCIt concept]
- Allogeneic CRISPR-Cas9 Engineered Anti-CD70 CAR-T Cells CTX131 [NCIt concept]
- Anti-CD19/Anti-CD70 4SCAR-expressing Bispecific T-cells [NCIt concept]
- Anti-CD27L Antibody-Drug Conjugate AMG 172 [NCIt concept]
- Anti-CD33/CD123/CD70 DARPin CD3 Engager MP0533 [NCIt concept]
- Anti-CD70 Antibody-Drug Conjugate MDX-1203 [NCIt concept]
- Anti-CD70 Antibody-drug Conjugate PRO1160 [NCIt concept]
- Anti-CD70 CAR-expressing T Lymphocytes [NCIt concept]
- Anti-CD70 Monoclonal Antibody IMM40H [NCIt concept]
- Anti-CD70 Monoclonal Antibody MDX-1411 [NCIt concept]
- Anti-CD70 Monoclonal Antibody SEA-CD70 [NCIt concept]
- Anti-GD2/Anti-CD70 4SCAR-expressing Bispecific T-cells [NCIt concept]
- Anti-PSMA/Anti-CD70 4SCAR-expressing Bispecific T-cells [NCIt concept]
- Anti-hCD70-CAR Retroviral Vector-transduced Autologous PBLs [NCIt concept]
- Autologous CXCR2-modified CD70 CAR T-cells [NCIt concept]
- Cusatuzumab [NCIt concept]
- Vorsetzumab Mafodotin [NCIt concept]

Keyword's position in hierarchy(ies) :

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