Soluble Tumor Necrosis Factor Receptor Superfamily Member 1A

Preferred Label : Soluble Tumor Necrosis Factor Receptor Superfamily Member 1A;

NCIt synonyms : sTNFRSF1A; sTNF RI; Soluble Tumor Necrosis Factor Receptor Superfamily Member I; sTNF-RI;

NCIt definition : Soluble tumor necrosis factor receptor superfamily member 1A ( 18 kDa) is encoded by the human TNFRSF1A gene. This enzymatically processed protein may be involved in the inhibition of binding and downstream signaling associated with binding of either tumor necrosis factor or lymphotoxin-alpha to the membrane-bound form of tumor necrosis factor receptor superfamily member 1A.;

NCI Metathesaurus CUI : CL545004;

Details

Origin ID

C147053;

UMLS CUI

C4554672;

OMIM relation
- Tumor necrosis factor receptor superfamily, member 1a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF1A Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Extracellular Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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