CD40LG wt Allele

Preferred Label : CD40LG wt Allele;

NCIt synonyms : CD40L; TRAP Gene; CD40LG; Tumor Necrosis Factor (Ligand) Superfamily Member 5 Gene; CD154; TNFSF5; HIGM1; TRAP; TNFSF5 wt Allele; hCD40L; Hyper-IgM Syndrome Gene; RP3-527F8.3; T-BAM; Tumor Necrosis Factor Ligand Superfamily, Member 5 Gene; IGM; IMD3; TNF Superfamily, Member 5 Gene; CD40 Ligand wt Allele; gp39; CD40 Ligand (TNF Superfamily, Member 5, Hyper-IgM Syndrome) Gene;

NCIt definition : Human CD40LG wild-type allele is located within Xq26 and is approximately 12 kb in length. This allele, which encodes CD40 ligand protein, plays a role in B-cell regulation, proliferation and adhesion.;

GenBank Accession Number : NM_000074;

Details

Origin ID

C50970;

UMLS CUI

C1706005;

OMIM relation
- Cd40 ligand [OMIM gene]
See also inter- (CISMeF)
- Hyper-IgM syndrome due to CD40 ligand deficiency [ICD-11 More detail]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Hyperimmunoglobulin M Syndrome [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- Xq26 [NCIt concept]
gene_is_element_in_pathway
- Allograft Rejection Pathway [NCIt concept]
- Antigen Dependent B Cell Activation Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Asthma Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- Bystander B Cell Activation Pathway [NCIt concept]
- CD40/CD40L Signaling Pathway [NCIt concept]
- CD40L Signaling Pathway [NCIt concept]
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_plays_role_in_process
- B-Cell Activation [NCIt concept]
- Cell Death Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Tumor Necrosis Factor Receptor Binding [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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