Tumor Necrosis Factor Receptor Superfamily Member 13C

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 13C;

NCIt synonyms : Prolixin; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; B Cell-Activating Factor Receptor; BLyS Receptor 3;

CISMeF acronym : BAFFR; BAFF-R;

NCIt definition : Tumor necrosis factor receptor superfamily member 13C (184 aa, 19 kDa) is encoded by the human TNFRSF13C gene. This protein plays a role in regulating the survival of peripheral B-cells.;

NCIt note : Tumor necrosis factor receptor superfamily member 13C ligands include tumor necrosis factor ligand superfamily member 13B (B-cell-activating factor; BAFF). (UniProt);

Details

Origin ID

C111797;

UMLS CUI

C1384654;

Automatic exact mappings (from CISMeF team)
- B-Cell activation factor receptor [MeSH concept]
- TNF receptor superfamily member 13C [ORDO Gene]
- Tumor necrosis factor receptor superfamily, member 13c [OMIM gene]
- b-cell activation factor receptor [MeSH Descriptor]
- fluphenazine [MeSH Descriptor]
- prolixin [MeSH concept]
- receptors, interleukin-4 [MeSH Descriptor]
OMIM relation
- Tumor necrosis factor receptor superfamily, member 13c [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TNFRSF13C protein, human [MeSH Supplementary Concept]
- TNFRSF13C protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF13C Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- B-Cell Immune Response Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Survival [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immunity [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- Anti-BAFFR Monoclonal Antibody ESG206 [NCIt concept]
- Autologous BAFF-expressing CAR T Cells LMY-920 [NCIt concept]
- Autologous BAFFR-targeting CAR T Cells [NCIt concept]

Keyword's position in hierarchy(ies) :

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