Tumor Necrosis Factor Receptor Superfamily Member 9

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 9;

NCIt synonyms : T-Cell Antigen 4-1BB Homolog; T Cell Antigen ILA; CD137; Receptor Protein 4-1BB; T-Cell Antigen ILA; CDw137; TNFRSF9; 4-1BB Ligand Receptor; CD137 Antigen;

NCIt definition : Tumor necrosis factor receptor superfamily member 9 (255 aa, 28 kDa) is encoded by the human TNFRSF9 gene. This protein plays a role in receptor signal transduction in activated T-lymphocytes.;

Details

Origin ID

C105113;

UMLS CUI

C0247111;

Automatic exact mappings (from CISMeF team)
- TNF superfamily member 9 [HGNC gene]
- Tumor Necrosis Factor Receptor Superfamily, Member 9 [MeSH Descriptor]
- Tumor Necrosis Factor Receptor Superfamily, Member 9 [MeSH concept]
- Tumor necrosis factor receptor superfamily, member 9 [OMIM gene]
OMIM relation
- Tumor necrosis factor receptor superfamily, member 9 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TNFRSF9 protein, human [MeSH Supplementary Concept]
- TNFRSF9 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF9 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- 4-1BB-Dependent Immune Response Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- Anti-4-1BB/PD-L1 Bispecific Antibody PM1003 [NCIt concept]
- Anti-CD137 Agonistic Monoclonal Antibody ADG106 [NCIt concept]
- Anti-CD137 Agonistic Monoclonal Antibody ADG206 [NCIt concept]
- Anti-CD137 Agonistic Monoclonal Antibody AGEN2373 [NCIt concept]
- Anti-CD137 Agonistic Monoclonal Antibody CTX-471 [NCIt concept]
- Anti-CD137 Agonistic Monoclonal Antibody EU101 [NCIt concept]
- Anti-CD137 Agonistic Monoclonal Antibody YH004 [NCIt concept]
- Anti-CD137 Monoclonal Antibody PE0116 [NCIt concept]
- Anti-CD137/Anti-FAP Bispecific Antibody BI 765179 [NCIt concept]
- Anti-CD228/4-1BB Bispecific Agent SGN-BB228 [NCIt concept]
- Anti-CEA/Anti-4-1BB Bispecific Antibody BGB-B167 [NCIt concept]
- Anti-Claudin18.2/Anti-4-1BB Bispecific Antibody PM1032 [NCIt concept]
- Anti-EpCAM/Anti-4-1BB Bispecific Antibody BNT314 [NCIt concept]
- Anti-HER2/4-1BB Bispecific Antibody YH32367 [NCIt concept]
- Anti-OX40/CD137 Bispecific Antibody FS120 [NCIt concept]
- Anti-PD-1/Anti-4-1BB Bispecific Antibody IBI-319 [NCIt concept]
- Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes [NCIt concept]
- CD137/Nectin-4 Bispecific-targeting Agent BT7480 [NCIt concept]
- CD137/PSMA/HSA Trispecific-targeting Agent CB 307 [NCIt concept]
- Cinrebafusp Alfa [NCIt concept]
- Delolimogene Mupadenorepvec [NCIt concept]
- Exlinkibart [NCIt concept]
- FAP/4-1BB-targeting DARPin MP0310 [NCIt concept]
- FAP/4-1BB-targeting Fusion Protein RO7122290 [NCIt concept]
- SIRPa-4-1BBL Fusion Protein DSP107 [NCIt concept]
- Urelumab [NCIt concept]
- Utomilumab [NCIt concept]
- Xirestomig [NCIt concept]

Keyword's position in hierarchy(ies) :

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