Tumor Necrosis Factor Receptor Superfamily Member 18

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 18;

NCIt synonyms : Activation-Inducible TNFR Family Receptor; CD357 Antigen; TNF Receptor Superfamily Activation-Inducible Protein; Glucocorticoid-Induced TNFR-Related Protein; GITR; TNFRSF18; Activation-Inducible TNFR Family Member;

NCIt definition : Tumor necrosis factor receptor superfamily member 18 (241 aa, 26 kDa) is encoded by the human TNFRSF18 gene. This protein is involved in T-cell-mediated immune function.;

Details

Origin ID

C105568;

UMLS CUI

C1455126;

Automatic exact mappings (from CISMeF team)
- Glucocorticoid-Induced TNFR-Related protein [MeSH concept]
- Tumor necrosis factor receptor superfamily, member 18 [OMIM gene]
- glucocorticoid-induced tnfr-related protein [MeSH Descriptor]
OMIM relation
- Tumor necrosis factor receptor superfamily, member 18 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TNFRSF18 protein, human [MeSH Supplementary Concept]
- TNFRSF18 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF18 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Survival [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- Anti-GITR Agonistic Monoclonal Antibody ASP1951 [NCIt concept]
- Anti-GITR Agonistic Monoclonal Antibody BMS-986156 [NCIt concept]
- Anti-GITR AgonisticMonoclonal Antibody REGN6569 [NCIt concept]
- Anti-GITR Monoclonal Antibody GWN 323 [NCIt concept]
- Anti-GITR Monoclonal Antibody MK-4166 [NCIt concept]
- Anti-human GITR Monoclonal Antibody AMG 228 [NCIt concept]
- Anti-human GITR Monoclonal Antibody TRX518 [NCIt concept]
- Efgivanermin Alfa [NCIt concept]
- Ragifilimab [NCIt concept]
- Trimeric GITRL-Fc OMP-336B11 [NCIt concept]

Keyword's position in hierarchy(ies) :

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