Tumor Necrosis Factor Ligand Superfamily Member 14

Preferred Label : Tumor Necrosis Factor Ligand Superfamily Member 14;

NCIt synonyms : Tumor Necrosis Factor Ligand 1D; Herpes Virus Entry Mediator Ligand; CD258; HVEM-L; LIGHT; Herpesvirus Entry Mediator Ligand; CD258 Antigen; TNFSF14;

NCIt definition : Tumor necrosis factor ligand superfamily member 14 (240 aa, 26 kDa) is encoded by the human TNFSF14 gene. This protein is involved in the regulation of both T-cell proliferation and apoptosis.;

NCIt note : The membrane bound form of tumor necrosis factor ligand superfamily member 14 acts as a receptor for Herpes simplex viruses.; Tumor necrosis factor ligand superfamily member 14 is a ligand for tumor necrosis factor receptor superfamily member 3 and a decoy receptor tumor necrosis factor receptor superfamily member 6B.; Tumor necrosis factor ligand superfamily member 14 can undergo proteolytic cleavage that generates a soluble form.;

Details

Origin ID

C133790;

UMLS CUI

C1570446;

Automatic exact mappings (from CISMeF team)
- Light [ICHI extension code]
- Light [ICHI target]
- Light [UNESCO concept]
- Light color (qualifier value) [SNOMED CT concept]
- Light, electromagnetic radiation (physical force) [SNOMED CT concept]
- Lighting [DeCS]
- Lighting [PASCAL theme]
- Lighting [UNESCO concept]
- Lights [ICD-11 Extension code]
- Tumor necrosis factor ligand superfamily, member 14 [OMIM gene]
- light [MeSH concept]
- light [ICF N2 Element]
- light [MeSH Descriptor]
- lighting [MeSH concept]
- lighting [MeSH Descriptor]
- tumor necrosis factor ligand superfamily member 14 [MeSH concept]
- tumor necrosis factor ligand superfamily member 14 [MeSH Descriptor]
OMIM relation
- Tumor necrosis factor ligand superfamily, member 14 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TNFSF14 protein, human [MeSH Supplementary Concept]
- TNFSF14 protein, human [MeSH concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- TNFSF14 Gene [NCIt concept]
- Tumor Necrosis Factor Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Signaling Protein [NCIt concept]
- Viral Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Death Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- T-Cell Proliferation [NCIt concept]
- Tumor Necrosis Factor Receptor Binding [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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