Tumor Necrosis Factor Receptor Superfamily Member 13B

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 13B;

NCIt synonyms : Tumor Necrosis Factor Receptor 13B; TACI; CD267 Antigen; Transmembrane Activator and CAML Interactor; TNFRSF13B;

NCIt definition : Tumor necrosis factor receptor superfamily member 13B (293 aa, 32 kDa) is encoded by the human TNFRSF13B gene. This protein plays a role in cytokine binding and lymphocyte activation.;

NCIt note : Tumor necrosis factor receptor superfamily member 13B ligands include tumor necrosis factor ligand superfamily member 13 (a proliferation-inducing ligand; APRIL) and tumor necrosis factor ligand superfamily member 13B (B-cell-activating factor; BAFF). (UniProt);

Details

Origin ID

C127903;

UMLS CUI

C0666480;

Automatic exact mappings (from CISMeF team)
- TNF receptor superfamily member 13B [ORDO Gene]
- Tumor necrosis factor receptor superfamily, member 13b [OMIM gene]
- transmembrane activator and caml interactor protein [MeSH Descriptor]
OMIM relation
- Tumor necrosis factor receptor superfamily, member 13b [OMIM gene]
See also inter- (CISMeF)
- TACI cells [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TNFRSF13B protein, human [MeSH Supplementary Concept]
- TNFRSF13B protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF13B Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immunity [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Lymphocyte Activation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- Autologous BAFF-expressing CAR T Cells LMY-920 [NCIt concept]
- Autologous BCMA/TACI-targeted CAR T Cells AUTO2 [NCIt concept]
- Autologous BCMA/TACI-targeted Trimeric APRIL-based CAR T Cells [NCIt concept]

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