" /> TNFRSF10B wt Allele - CISMeF





Preferred Label : TNFRSF10B wt Allele;

NCIt synonyms : ZTNFR9; TRICK2A; TRAILR2; Tumor Necrosis Factor Receptor Superfamily, Member 10B wt Allele; TRICKB; TRICK2B; DR5; KILLER/DR5; TRICK2; KILLER; TRAIL-R2; CD262; UNQ160/PRO186;

NCIt definition : Human TNFRSF10B wild-type allele is located within 8p22-p21 and is approximately 49 kb in length. This allele, which encodes tumor necrosis factor receptor superfamily member 10B protein, plays a role in tumor necrosis factor-related apoptosis signal mediation.;

NCIt note : Head and neck squamous cell carcinoma may be linked to a 2-bp insertion in the TNFRSF10B gene at residue 1065, which introduces a premature stop codon and results in a truncated protein. (OMIM);

GenBank Accession Number : NM_003842;

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31/07/2025


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