Ectodysplasin-A1

Preferred Label : Ectodysplasin-A1;

NCIt synonyms : Ectodysplasin-A; EDA1; Ectodysplasin A Isoform 1; Ectodysplasin A1; Ectodysplasin A; EDA-A1; Ectodermal Dysplasia Protein 4; X-Linked Anhidroitic Ectodermal Dysplasia Protein; Ectodysplasin A1 Isoform; EDA Protein; Ectodysplasin-A Isoform 1; Tumor Necrosis Factor Ligand 7C; ED1-A1;

NCIt definition : Ectodysplasin-A1 (391 aa, 41 kDa) is encoded by the human EDA gene. This protein plays a role in the positive regulation of signaling mediated by tumor necrosis factor receptor superfamily member EDAR.;

NCIt note : Ectodysplasin-A1 is processed by furin to yield a secreted form.; UniProt considers isoform 1A to be the canonical form of ectodysplasin-A. Ectodysplasin-A1 is a ligand for EDAR.;

Détails

Origin ID

C159359;

UMLS CUI

C5202873;

Automatic exact mappings (from CISMeF team)
- Ectodysplasin a [OMIM gene]
- ectodysplasin A [ORDO Gene]
- ectodysplasin A [HGNC gene]
- ectodysplasin A, isoform 1 [MeSH concept]
- ectodysplasins [MeSH concept]
- ectodysplasins [MeSH Descriptor]
OMIM relation
- Ectodysplasin a [OMIM gene]
See also inter- (CISMeF)
- Ectodermal dysplasia 1, hypohidrotic, X-linked [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- EDA Gene [NCIt concept]
- Tumor Necrosis Factor Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Death Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Tumor Necrosis Factor Receptor Binding [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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