Tumor Necrosis Factor Receptor Superfamily Member 12A

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 12A;

NCIt synonyms : FGF-Inducible 14; Tweak Receptor; CD266; Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14; Tweak-Receptor; CD266 Antigen; TweakR; Type I Transmembrane Protein Fn14;

NCIt definition : Tumor necrosis factor receptor superfamily member 12A (129 aa, 14 kDa) is encoded by the human TNFRSF12A gene. This protein is involved in both apoptosis and angiogenesis.;

Details

Origin ID

C117073;

UMLS CUI

C1438619;

Automatic exact mappings (from CISMeF team)
- TWEAK Receptor [MeSH Descriptor]
- TWEAK Receptor [MeSH concept]
- Tumor necrosis factor receptor superfamily, member 12a [OMIM gene]
OMIM relation
- Tumor necrosis factor receptor superfamily, member 12a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TNFRSF12A protein, human [MeSH Supplementary Concept]
- TNFRSF12A protein, human [MeSH concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF12A Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Angiogenesis Promoter [NCIt concept]
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Positive Regulation of Angiogenesis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Induction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- Enavatuzumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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