Tumor Necrosis Factor Ligand Superfamily Member 18

Preferred Label : Tumor Necrosis Factor Ligand Superfamily Member 18;

NCIt synonyms : Tumor Necrosis Factor Ligand 2A; GITR Ligand; Tumor Necrosis Factor Superfamily Member 18; Activation-Inducible TNF-Related Ligand; Glucocorticoid-Induced TNF-Related Ligand; hGITRL; TNFSF18; AITRL; AITR Ligand; Glucocorticoid-Induced TNFR-Related Protein Ligand;

NCIt definition : Tumor necrosis factor ligand superfamily member 18 (199 aa, 23 kDa) is encoded by the human TNFSF18 gene. This protein plays a role in the positive regulation of both activation and proliferation of T-cells.;

Details

Origin ID

C142776;

UMLS CUI

C1313262;

Automatic exact mappings (from CISMeF team)
- Tumor necrosis factor ligand superfamily, member 18 [OMIM gene]
OMIM relation
- Tumor necrosis factor ligand superfamily, member 18 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TNFSF18 protein, human [MeSH Supplementary Concept]
- TNFSF18 protein, human [MeSH concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- TNFSF18 Gene [NCIt concept]
- Tumor Necrosis Factor Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Endothelial Cell [NCIt concept]
- Extracellular Space [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Death Process [NCIt concept]
- Chemotaxis Induction [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Leukocyte Trafficking Induction [NCIt concept]
- T-Cell Activation [NCIt concept]
- T-Cell Proliferation [NCIt concept]
- Tumor Necrosis Factor Receptor Binding [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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