Tumor Necrosis Factor Ligand Superfamily Member 4

Preferred Label : Tumor Necrosis Factor Ligand Superfamily Member 4;

NCIt synonyms : CD134 Ligand; OX40L; CD252; OX40 Ligand; TNFSF4; Glycoprotein 34; CD252 Antigen; Glycoprotein Gp34; Antigen CD252; OX40 Antigen Ligand; TAX Transcriptionally-Activated Glycoprotein 1;

NCIt definition : Tumor necrosis factor ligand superfamily member 4 (183 aa, 21 kDa) is encoded by the human TNFSF4 gene. This protein is involved in the stimulation of both T-cell proliferation and cytokine production.;

Details

Origin ID

C20532;

UMLS CUI

C0257572;

Currated CISMeF NLP mapping
- OX40 ligand [MeSH concept]
- ox40 ligand [MeSH Descriptor]
OMIM relation
- Tumor necrosis factor ligand superfamily, member 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TNFSF4 protein, human [MeSH concept]
- TNFSF4 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- TNFSF4 Gene [NCIt concept]
- Tumor Necrosis Factor Family Gene [NCIt concept]
gene_product_expressed_in_tissue
- Heart [NCIt concept]
- Spleen [NCIt concept]
- Thymus Gland [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- T-Lymphocyte [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- OX40 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Death Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- T-Cell Activation [NCIt concept]
- Tumor Necrosis Factor Receptor Binding [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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