Soluble Tumor Necrosis Factor Receptor Superfamily Member 9

Preferred Label : Soluble Tumor Necrosis Factor Receptor Superfamily Member 9;

NCIt synonyms : sTNFRSF9; Soluble 4-1BB; Soluble 4-1BB Ligand Receptor; Soluble Receptor Protein 4-1BB; sCD137; s4-1BB; Soluble T-Cell Antigen ILA; Soluble TNFRSF9; Soluble CD137 Antigen; Soluble T-Cell Antigen 4-1BB Homolog; Soluble CD137; sILA;

NCIt definition : Soluble tumor necrosis factor receptor superfamily member 9 is encoded by the human TNFRSF9 gene. This protein plays a role in both activation-induced cell death (AICD) of T-lymphocytes and negative feedback control of inflammation.;

NCIt note : Expression of soluble tumor necrosis factor receptor superfamily member 9 (sTNFRSF9) does not result from proteolytic processing of the full-length membrane-bound TNFRSF9 but appears to result from the translation of alternatively spliced TNFRSF9 mRNAs. (Cytokine. 2000; 12: 742-746.);

NCI Metathesaurus CUI : CL556864;

Details

Origin ID

C153501;

UMLS CUI

C4727299;

OMIM relation
- Tumor necrosis factor receptor superfamily, member 9 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF9 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Negative Regulation of Inflammatory Response Process [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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