TNFSF10 wt Allele

Preferred Label : TNFSF10 wt Allele;

NCIt synonyms : TL2; TRAIL; APO2L; Tumor Necrosis Factor (Ligand) Superfamily, Member 10 wt Allele; CD253; Tumor Necrosis Factor Ligand Superfamily, Member 10 Gene; Tumor Necrosis Factor (Ligand) Family, Member 10 Gene;

NCIt related terms : Apo-2L;

NCIt definition : Human TNFSF10 wild-type allele is located within 3q26 and is approximately 18 kb in length. This allele, which encodes tumor necrosis factor ligand superfamily member 10 protein, is involved in the induction and modulation of apoptosis.;

Alternative definition : NCI-GLOSS: A cell protein that can attach to certain molecules in some cancer cells and may kill the cells. Apo-2L is being studied in the treatment of cancer.;

GenBank Accession Number : NM_003810;

Codes from synonyms : CDR0000641163;

Détails

Origin ID

C50962;

UMLS CUI

C1705952;

OMIM relation
- Tumor necrosis factor ligand superfamily, member 10 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q26 [NCIt concept]
gene_is_element_in_pathway
- Apoptosis Pathway [NCIt concept]
- Caspase Cascade in Apoptosis [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- DR3 and DR4/5 Mediated Apoptosis Pathway [NCIt concept]
- FOXO Transcription Factor Family Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- TRAIL Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Cell Death Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Tumor Necrosis Factor Receptor Binding [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

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