TNFSF12 wt Allele

Preferred Label : TNFSF12 wt Allele;

NCIt synonyms : TWEAK; APO3L; DR3LG; Tumor Necrosis Factor Ligand Superfamily, Member 12 Gene; UNQ181/PRO207; Tumor Necrosis Factor (Ligand) Superfamily, Member 12 wt Allele;

NCIt definition : Human TNFSF12 wild-type allele is located in the vicinity of 17p13 and is approximately 13 kb in length. This allele, which encodes tumor necrosis factor ligand superfamily member 12 protein, is involved in the promotion of angiogenesis. A readthrough that fuses this gene and the neighboring TNFSF13 gene may be expressed in activated T-cells and T- or B-cell lymphoma.;

GenBank Accession Number : AF030099;

Details

Origin ID

C117067;

UMLS CUI

C3889965;

Automatic exact mappings (from CISMeF team)
- Cytokine TWEAK [MeSH Descriptor]
- TNF superfamily member 12 [ORDO Gene]
- Tumor necrosis factor ligand superfamily, member 12 [OMIM gene]
OMIM relation
- Tumor necrosis factor ligand superfamily, member 12 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17p13 [NCIt concept]
gene_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- DR3 and DR4/5 Mediated Apoptosis Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Cell Death Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Positive Regulation of Angiogenesis [NCIt concept]
- Signal Transduction Induction [NCIt concept]
- Tumor Necrosis Factor Receptor Binding [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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