Adiponectin - CISMeF

Preferred Label : Adiponectin;

NCIt synonyms : 30 kDa Adipocyte Complement-Related Protein; ACRP30; Gelatin-Binding Protein; Adipose Most Abundant Gene Transcript 1 Protein; Adipocyte, C1q and Collagen Domain-Containing Protein; apM-1; Adipocyte Complement-Related 30 kDa Protein; Gelatin-Binding Protein, 28-kD; Adipocyte-Specific Secretory Protein;

NCIt definition : Adiponectin (244 aa, 26 kDa) is encoded by the human ADIPOQ gene. This protein is involved in the modulation of both glucose metabolism and lipid homeostasis.;

NCIt note : Adiponectin can be found in plasma as trimers (low molecular weight complexes or LMW), hexamers (middle molecular weight complexes or MMW) and 12- to 18-mers (higher molecular weight or HMW). MMW and HMW complexes are made up of disulfide-linked trimers. (UniProt);

Details

Origin ID

C94786;

UMLS CUI

C1438411;

Currated CISMeF NLP mapping
- Adiponectin [LOINC component]
- Adiponectin (substance) [SNOMED CT concept]
- adiponectin [MeSH Descriptor]
- adiponectin [MeSH concept]
- gelatin binding protein [MeSH concept]
- gelatin binding protein [MeSH Supplementary Concept]
OMIM relation
- Adipocyte-, c1q-, and collagen domain-containing [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ADIPOQ protein, human [MeSH concept]
- ADIPOQ protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ADIPOQ Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_has_associated_anatomy
- Adipocyte [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Metabolic Syndrome Pathway [NCIt concept]
- PPAR Signaling Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Type 2 Diabetes Mellitus [NCIt concept]
gene_product_plays_role_in_biological_process
- Cholesterol Homeostasis [NCIt concept]
- Gluconeogenesis Inhibition [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Negative Regulation of Inflammatory Response Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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