Tumor Necrosis Factor Receptor Superfamily Member 10D

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 10D;

NCIt synonyms : TNFRSF10D; CD264; TNF Receptor Superfamily Member 10d; TNF Receptor-Related Receptor for TRAIL; CD264 Antigen; DcR2; TRAIL Receptor with a Truncated Death Domain; Decoy Receptor 2; TNF-Related Apoptosis-Inducing Ligand Receptor 4; TRAIL-R4; TRAIL Receptor 4;

NCIt definition : Tumor necrosis factor receptor superfamily member 10D (386 aa, 42 kDa) is encoded by the human TNFRSF10D gene. This protein plays a role in cell survival.;

NCIt note : Tumor necrosis factor receptor superfamily member 10D is a decoy receptor for tumor necrosis factor superfamily member 10 because it has a truncated cytoplasmic death domain. Therefore, it does not induce apoptosis.;

Details

Origin ID

C159373;

UMLS CUI

C1310460;

Automatic exact mappings (from CISMeF team)
- C-C motif chemokine receptor 6 [ORDO Gene]
- TNF receptor superfamily member 10d [HGNC gene]
- Tumor necrosis factor receptor superfamily, member 10d [OMIM gene]
- receptors, tnf-related apoptosis-inducing ligand [MeSH Descriptor]
OMIM relation
- Tumor necrosis factor receptor superfamily, member 10d [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TNFRSF10D protein, human [MeSH Supplementary Concept]
- TNFRSF10D protein, human [MeSH concept]
- receptors, tumor necrosis factor, member 10d [MeSH concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF10D Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Inhibitor [NCIt concept]
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- TRAIL Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients