Tumor Necrosis Factor Receptor Superfamily Member 16

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 16;

NCIt synonyms : NGFR; Low Affinity Neurotrophin Receptor p75NTR; p75 (NTR); CD271 Antigen; Antigen CD271; NGF Receptor; p75(NTR); Low Affinity Nerve Growth Factor Receptor; p75NTR; Gp80-LNGFR; Low-Affinity Nerve Growth Factor Receptor; CD271; Nerve Growth Factor Receptor; NGF-R; NGF R;

NCIt definition : Tumor necrosis factor receptor superfamily member 16 (427 aa, 45 kDa) is encoded by the human NGFR gene. This protein plays a role in neurotrophin binding and signal transduction.;

NCIt note : NGFR binds at low affinity to NGF, BDNF, NTF3, and NTF4. (UniProt);

Details

Origin ID

C17342;

UMLS CUI

C1435659;

Currated CISMeF NLP mapping
- receptor, nerve growth factor [MeSH Descriptor]
- receptor, nerve growth factor [MeSH concept]
- receptors, nerve growth factor [MeSH Descriptor]
- receptors, nerve growth factor [MeSH concept]
False automatic mappings
- Adapalene [MeSH Descriptor]
OMIM relation
- Nerve growth factor receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- NGFR protein, human [MeSH concept]
- NGFR protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- NGFR Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
- Growth Factor Receptor [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Death Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Apoptosis Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- MAP Kinase Downregulation Pathway [NCIt concept]
- Nerve Growth Factor Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- NGFR-transduced Autologous T Lymphocytes [NCIt concept]

Keyword's position in hierarchy(ies) :

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