Tumor Necrosis Factor Receptor Superfamily Member 1B

Preferred Label : Tumor Necrosis Factor Receptor Superfamily Member 1B;

NCIt synonyms : Tumor Necrosis Factor Receptor 2; Tumor Necrosis Factor Binding Protein 2; Tumor Necrosis Factor Beta Receptor; p75; TNFR, 75-kD; Tumor Necrosis Factor Receptor Type II; p75 TNF Receptor; TNF-RII; TNF-R-II; CD120b Antigen; TNF-R2; p80 TNF-Alpha Receptor; TNFR, 80-kD; TNFR-II; TNFRSF1B;

NCIt definition : Tumor necrosis factor receptor superfamily member 1B (461 aa, 48 kDa) is encoded by the human TNFRSF1B gene. This protein plays a role in tumor necrosis factor signaling and the negative regulation of apoptosis.;

Details

Origin ID

C18487;

UMLS CUI

C1447786;

OMIM relation
- Tumor necrosis factor receptor subfamily, member 1b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TNFRSF1B protein, human [MeSH concept]
- TNFRSF1B protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TNF Receptor Family Gene [NCIt concept]
- TNFRSF1B Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- TNFR2 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Death Signaling Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Necrosis Factor Signaling Process [NCIt concept]
is_target
- Anti-TNFR2 Monoclonal Antibody BI-1808 [NCIt concept]
- Anti-TNFR2 Monoclonal Antibody BI-1910 [NCIt concept]
- Anti-TNFR2 Monoclonal Antibody NBL-020 [NCIt concept]
- Anti-TNFR2 Monoclonal Antibody SIM1811-03 [NCIt concept]
- Emunkitug [NCIt concept]

Keyword's position in hierarchy(ies) :

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