" /> Anti-TNFR2 Monoclonal Antibody HFB200301 - CISMeF





Preferred Label : Anti-TNFR2 Monoclonal Antibody HFB200301;

NCIt synonyms : Anti-TNFR2 Agonist Antibody HFB200301;

NCIt definition : A humanized agonistic monoclonal antibody directed against tumor necrosis factor receptor 2 (TNFR2; tumor necrosis factor receptor superfamily member 1B; TNFRSF1B), with potential antineoplastic activity. Upon administration, anti-TNFR2 monoclonal antibody HFB200301 targets and binds to TNFR2 expressed on the surface of CD4 T-cells, CD8 T-cells and natural killer (NK) cells in the tumor micro-environment (TME), thereby activating CD4 T-cells, CD8 T-cells and NK cells. This may enhance T-cell- and NK cell- mediated immune responses against tumor cells. TNFR2, a member of the TNFR family of co-stimulatory molecules, plays an important role in T-cell co-stimulation.;

Molecule name : HFB 200301; HFB-200301;

NCI Metathesaurus CUI : CL1791930;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
12/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.