Protein DJ-1 - CISMeF

Preferred Label : Protein DJ-1;

NCIt synonyms : Oncogene DJ1; PARK7; Parkinson Disease Protein 7; EC 3.4.-.-;

NCIt definition : Protein DJ-1 (189 aa, 20 kDa) is encoded by the human PARK7 gene. This protein plays a role in the downregulation of apoptosis.;

NCIt note : Protein DJ-1 shares homology with the peptidase C56 family of proteins but may not have proteolytic activity. (UniProt);

Details

Origin ID

C104716;

UMLS CUI

C0537311;

Automatic exact mappings (from CISMeF team)
- Oncogene dj1 [OMIM gene]
- Parkinson disease 7, autosomal recessive early-onset [OMIM Phenotype]
- Parkinsonism associated deglycase [ORDO Gene]
- Protein Deglycase DJ-1 [MeSH Descriptor]
OMIM relation
- Oncogene dj1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PARK7 protein, human [MeSH concept]
- PARK7 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- PARK7 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Inhibitor [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
- Parkinson's Disease Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]

Keyword's position in hierarchy(ies) :

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