NEDD8-Activating Enzyme E1 Regulatory Subunit

Preferred Label : NEDD8-Activating Enzyme E1 Regulatory Subunit;

NCIt synonyms : Amyloid Protein-Binding Protein 1; APP-BP1; Amyloid Beta Precursor Protein-Binding Protein 1, 59 kDa; Proto-Oncogene Protein 1;

NCIt definition : NEDD8-activating enzyme E1 regulatory subunit (534 aa, 60 kDa) is encoded by the human NAE1 gene. This protein plays a role in the mediation of protein neddylation.;

Details

Origin ID

C95855;

UMLS CUI

C3272392;

Automatic exact mappings (from CISMeF team)
- Nedd8-activating enzyme e1, subunit 1 [OMIM gene]
OMIM relation
- Nedd8-activating enzyme e1, subunit 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Pediatric Oncology Biomarkers/Targets Associated with Other Relevant Evidence [NCIt concept]
gene_encodes_gene_product
- NAE1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- NEDD8 Activating Enzyme [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Cycle Checkpoint [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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