Tumor Necrosis Factor Alpha-Induced Protein 3

Preferred Label : Tumor Necrosis Factor Alpha-Induced Protein 3;

NCIt synonyms : OTU Domain-Containing Protein 7C; TNF Alpha-Induced Protein 3; EC 6.3.2.-, Formerly; Putative DNA-Binding Protein A20; Zinc Finger Protein A20; EC 3.4.19.12; TNFAIP3; EC 2.3.2.-; Tumor Necrosis Factor Alpha Inducible Protein A20;

NCIt definition : Tumor necrosis factor alpha-induced protein 3 (790 aa, 90 kDa) is encoded by the human TNFAIP3 gene. This protein may play a role in the regulation of apoptosis.;

NCIt note : Tumor necrosis factor alpha-induced protein 3 has both ubiquitin ligase and deubiquitinase activities. (UniProt);

Details

Origin ID

C84996;

UMLS CUI

C0171965;

OMIM relation
- Tumor necrosis factor-alpha-induced protein 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
UMLS correspondences (same concept)
- TNFAIP3 protein, human [MeSH concept]
- TNFAIP3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TNFAIP3 Gene [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
gene_product_is_element_in_pathway
- CD40/CD40L Signaling Pathway [NCIt concept]
- CD40L Signaling Pathway [NCIt concept]
- Canonical NF-kappaB Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- TNFR2 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Deubiquitination [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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