" /> HRK wt Allele - CISMeF





Preferred Label : HRK wt Allele;

NCIt synonyms : DP5; Harakiri wt Allele;

NCIt definition : Human HRK wild-type allele is located in the vicinity of 12q24.23 and is less than 1 kb in length. This allele, which encodes activator of apoptosis harakiri protein, is involved in the regulation of apoptosis.;

NCIt note : Design Note: HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXLHRK regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L).;

GenBank Accession Number : NM_003806;

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12/05/2024


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