SFRP1 wt Allele

Preferred Label : SFRP1 wt Allele;

NCIt synonyms : FRP-1; Secreted Frizzled-Related Protein 1 wt Allele; FrzA; FRP1; SARP2; FRP;

NCIt definition : Human SFRP1 wild-type allele is located in the vicinity of 8p11.21 and is approximately 48 kb in length. This allele, which encodes secreted frizzled-related protein 1, plays a role in the modulation of Wnt signaling. Methylation of the gene is associated with decreased expression and may be a factor in both colon and breast cancer.;

GenBank Accession Number : AF017987;

Details

Origin ID

C95301;

UMLS CUI

C2987045;

OMIM relation
- Secreted frizzled-related protein 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8p11.21 [NCIt concept]
gene_is_element_in_pathway
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Bone Remodeling [NCIt concept]
- Environment-to-Cell Communication [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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