" /> Omacetaxine Mepesuccinate - CISMeF





Preferred Label : Omacetaxine Mepesuccinate;

NCIt synonyms : Cephalotaxine, 4-Methyl 2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate (Ester); HHT;

NCIt related terms : homoharringtonine; Cephalotaxine, 4-methyl 2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate (ester), [3(R)]- (9CI);

NCIt definition : A semisynthetic formulation of the cytotoxic plant alkaloid homoharringtonine isolated from the evergreen tree Cephalotaxus with potential antineoplastic activity. Omacetaxine binds to the 80S ribosome in eukaryotic cells and inhibits protein synthesis by interfering with chain elongation. This agent also induces differentiation and apoptosis in some cancer cell types.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the plant alkaloid family of drugs.;

UNII : 6FG8041S5B;

InChIKey : HYFHYPWGAURHIV-JFIAXGOJSA-N;

CAS number : 26833-87-4;

Drug name : Ceflatonin; Synribo; Omapro;

Molecule name : CGX-635;

Chemical formula : C29H39NO9;

NSC code : 141633;

Codes from synonyms : NSC0141633; CDR0000045216;

Détails


Position du mot-clé dans l'(les) arborescence(s) : arborescence

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31/07/2025


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