CASP8-Associated Protein 2

Preferred Label : CASP8-Associated Protein 2;

NCIt synonyms : Caspase 8-Associated Protein 2; Human FLASH; CASP8 Associated Protein 2; FLICE-Associated Huge Protein; FLASH Homolog RIP25;

NCIt definition : CASP8-associated protein 2 (1982 aa, 223 kDa) is encoded by the human CASP8AP2 gene. This protein is involved in the positive regulation of caspase-dependent apoptosis.;

Details

Origin ID

C126619;

UMLS CUI

C4284125;

Automatic exact mappings (from CISMeF team)
- Caspase 8-associated protein 2 [OMIM gene]
- caspase 8 associated protein 2 [HGNC gene]
OMIM relation
- Caspase 8-associated protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- CASP8AP2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrion [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Caspase Activation [NCIt concept]
- Caspase-Dependent Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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