" /> RIPK1 wt Allele - CISMeF





Preferred Label : RIPK1 wt Allele;

NCIt synonyms : RIP; Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1 wt Allele; RIP1; FLJ39204;

NCIt definition : Human RIPK1 wild-type allele is located in the vicinity of 6p25.2 and is approximately 37 kb in length. This allele, which encodes receptor-interacting serine/threonine-protein kinase 1 protein, is involved in positive regulation of apoptosis and activation of the transcription factor NF-kappa-B. The RIPK1 gene is down-regulated in mantle cell lymphomas.;

NCIt note : The RIPK1 gene plays a critical role in DNA damage-induced, p53-independent cell death.;

GenBank Accession Number : NM_003804;

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15/05/2024


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