AGTR2 wt Allele

Preferred Label : AGTR2 wt Allele;

NCIt synonyms : AT2; Angiotensin II Receptor, Type 2 wt Allele; MRX88; ATGR2;

NCIt definition : Human AGTR2 wild-type allele is located within Xq22-q23 and is approximately 4 kb in length. This allele, which encodes type-2 angiotensin II receptor protein, plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system, apoptosis and G-protein receptor coupled signal transduction.;

GenBank Accession Number : NM_000686;

Details

Origin ID

C51400;

UMLS CUI

C1705845;

OMIM relation
- Angiotensin II receptor, type 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- X: 115113885-115117702 [NCIt concept]
gene_in_chromosomal_location
- Xq22-q23 [NCIt concept]
gene_is_element_in_pathway
- Angiotensin-converting Enzyme 2 Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- Cardiac Hypertrophy Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- Renin-Angiotensin Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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