Protein Kinase C Epsilon Type

Preferred Label : Protein Kinase C Epsilon Type;

NCIt synonyms : nPKC-Epsilon; EC 2.7.11.13;

NCIt definition : Protein kinase C epsilon type (737 aa, 84 kDa) is encoded by the human PRKCE gene. This protein plays a role in diacylglycerol-dependent serine/threonine phosphorylation.;

Details

Origin ID

C114339;

UMLS CUI

C1566340;

Automatic exact mappings (from CISMeF team)
- calcium-independent protein kinase C [MeSH Supplementary Concept]
- nPKC-epsilon [MeSH concept]
- protein kinase C activity [GO term]
OMIM relation
- Protein kinase C, epsilon [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PRKCE protein, human [MeSH Supplementary Concept]
- PRKCE protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PRKCE Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Protein Kinase C [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- DAG/PE-Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Centrosome Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Flumazenil Cardioprotection Pathway [NCIt concept]
- IL2-Mediated Signaling Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor 4 Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Immune System Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Synthetic Plumbagin PCUR-101 [NCIt concept]

Keyword's position in hierarchy(ies) :

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