TNF Receptor-Associated Factor 1

Preferred Label : TNF Receptor-Associated Factor 1;

NCIt synonyms : TRAF1; Epstein-Barr Virus-Induced Protein 6;

NCIt definition : TNF receptor-associated factor 1 (416 aa, 46 kDa) is encoded by the human TRAF1 gene. This protein plays a role in the regulation of both protein ubiquitination and TNF receptor family-mediated signaling pathways.;

Details

Origin ID

C105110;

UMLS CUI

C4281730;

Automatic exact mappings (from CISMeF team)
- TNF Receptor-Associated factor 1 [MeSH Descriptor]
- TNF Receptor-Associated factor 1 [MeSH concept]
- Tnf receptor-associated factor 1 [OMIM gene]
OMIM relation
- Tnf receptor-associated factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- TRAF1 Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_is_element_in_pathway
- CD40/CD40L Signaling Pathway [NCIt concept]
- HIV-1 Nef: Negative Effector Pathway for Fas and TNF-Alpha [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- TNFR2 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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