Interferon Regulatory Factor 1

Preferred Label : Interferon Regulatory Factor 1;

NCIt synonyms : IRF-1; IRF1; Interferon Regulatory Factor-1;

NCIt definition : Interferon regulatory factor 1 (325 aa, 37 kDa) is encoded by the human IRF1 gene. This protein plays a role in the regulation of interferon gene expression.;

Details

Origin ID

C26627;

UMLS CUI

C1530270;

Currated CISMeF NLP mapping
- interferon regulatory Factor-1 [MeSH Descriptor]
- interferon regulatory Factor-1 [MeSH concept]
OMIM relation
- Interferon regulatory factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IRF1 protein, human [MeSH concept]
- IRF1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- IRF1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- IFN-Beta Enhancer Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL6-Mediated Signaling Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Telomerase Regulation Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Acute Myeloid Leukemia [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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