Acute Myeloid Leukemia

Preferred Label : Acute Myeloid Leukemia;

NCIt synonyms : AML; AML - Acute Myeloid Leukemia; Hematopoeitic - Acute Myleogenous Leukemia (AML); Acute Myelogenous Leukemias; ANLL;

NCIt related terms : Acute Myeloid Leukemia (AML); acute myeloblastic leukemia; acute myelogenous leukemia; Acute myelocytic leukemia; Acute granulocytic leukemia; acute nonlymphocytic leukemia;

NCIt definition : A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias (AMLs) encompasses four major categories: 1) AML with recurrent genetic abnormalities; 2) AML with multilineage dysplasia; 3) Therapy-related AML; 4) AML not otherwise specified. The required bone marrow or peripheral blood blast percentage for the diagnosis of AML is 20% (WHO classification).;

Alternative definition : NICHD: A rapidly progressive cancer of the blood and bone marrow consisting of the proliferation of abnormal myeloblasts, which are immature, dysfunctional white blood cells.; NCI-GLOSS: An aggressive (fast-growing) disease in which too many myeloblasts (immature white blood cells that are not lymphoblasts) are found in the bone marrow and blood.;

Neoplastic status : Malignant;

ICD-O code : 9861/3;

Codes from synonyms : CDR0000046347; CDR0000044363; CDR0000575436; CDR0000575435; CDR0000046215; CDR0000046757;

Details

Origin ID

C3171;

UMLS CUI

C0023467;

Automatic exact mappings (from CISMeF team)
- Acute granulocytic leukemia [MedDRA LLT]
- Acute myelocytic leukemia [MedDRA LLT]
- Acute myelogenous leukemia [PASCAL descriptor]
- Acute myeloid leukaemia, NOS [ICD-11 Extension code]
- Acute myeloid leukaemias and related precursor neoplasms [ICD-11 Category]
- Acute myeloid leukemia - category (morphologic abnormality) [SNOMED CT concept]
- Acute nonlymphocytic leukemia [PASCAL descriptor]
- Myeloid leukemia, subacute [MedDRA LLT]
Currated CISMeF NLP mapping
- Acute myeloblastic leukaemia [MedDRA LLT]
- Acute myeloblastic leukemia [ICD-10 Sub-category]
- Acute myeloblastic leukemia [MedDRA LLT]
- Acute myeloid leukaemia [ICD-10 Sub-category (who)]
- Acute myeloid leukaemia [MedDRA Preferred Term]
- Acute myeloid leukaemia NOS [MedDRA LLT]
- Acute myeloid leukemia [ICD-9 code]
- Acute myeloid leukemia [HPO term]
- Acute myeloid leukemia [ICD-O code]
- Acute myeloid leukemia [ORDO Disease]
- Acute myeloid leukemia [MedDRA LLT]
- Acute myeloid leukemia (disorder) [SNOMED CT concept]
- Acute myeloid leukemia NOS [MedDRA LLT]
- Acute myeloid leukemia, no International Classification of Diseases for Oncology subtype (morphologic abnormality) [SNOMED CT concept]
- Leukaemia myeloblastic acute [MedDRA LLT]
- Leukaemias acute myeloid [MedDRA High Level Term]
- Leukemia myeloblastic acute [MedDRA LLT]
- Leukemia, acute myeloid [OMIM Phenotype]
- Myeloid leukaemia, acute [MedDRA LLT]
- Myeloid leukemia, acute [ICD-9 code]
- Myeloid leukemia, acute [MedDRA LLT]
- acute myeloid leukemia [DO Concept]
- acute myeloid leukemia [Disease (Nov.)]
- acute myeloid leukemia [SNOMED Notion]
- acute myeloid leukemia [MedlinePlus Topic]
- leukemia, myeloid, acute [MeSH Descriptor]
- leukemia, myeloid, acute [MeSH concept]
DO Cross reference
- acute myeloid leukemia [DO Concept]
Disease excludes abnormal cell
- Neoplastic Lymphoblast [NCIt concept]
Disease excludes normal cell origin
- Lymphocyte [NCIt concept]
False automatic mappings
- Acute myeloid leukaemia (in remission) [MedDRA Preferred Term]
- Acute myeloid leukemia (in remission) [MedDRA LLT]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Acute granulocytic leukaemia [MedDRA LLT]
- Acute granulocytic leukemia [MedDRA LLT]
- Acute megakaryocytic leukemia [HPO term]
- Acute myeloblastic leukaemia [MedDRA LLT]
- Acute myeloblastic leukemia [MedDRA LLT]
- Acute myeloblastic leukemia [ICD-10 Sub-category]
- Acute myelocytic leukaemia [MedDRA LLT]
- Acute myelocytic leukemia [MedDRA LLT]
- Acute myeloid leukaemia [MedDRA Preferred Term]
- Acute myeloid leukaemia [ICD-10 Sub-category (who)]
- Acute myeloid leukaemia NOS [MedDRA LLT]
- Acute myeloid leukemia [MedDRA LLT]
- Acute myeloid leukemia [ORDO Disease]
- Acute myeloid leukemia [ICD-O code]
- Acute myeloid leukemia [HPO term]
- Acute myeloid leukemia [LOINC component]
- Acute myeloid leukemia (disorder) [SNOMED CT concept]
- Acute myeloid leukemia (morphologic abnormality) [SNOMED CT concept]
- Acute myeloid leukemia - category (morphologic abnormality) [SNOMED CT concept]
- Acute myeloid leukemia NOS [MedDRA LLT]
- Acute myeloid leukemia, no International Classification of Diseases for Oncology subtype (morphologic abnormality) [SNOMED CT concept]
- Leukaemia myeloblastic acute [MedDRA LLT]
- Leukaemias acute myeloid [MedDRA High Level Term]
- Leukemia myeloblastic acute [MedDRA LLT]
- Leukemia, acute myeloid [OMIM Phenotype]
- Myeloid leukaemia, acute [MedDRA LLT]
- Myeloid leukemia, acute [MedDRA LLT]
- Myeloid leukemia, acute [ICD-9 code]
- Non-lymphoblastic leukaemia acute [MedDRA LLT]
- Non-lymphoblastic leukemia acute [MedDRA LLT]
- acute myeloid leukemia [DO Concept]
- acute myeloid leukemia [Disease (Nov.)]
- acute myeloid leukemia [MedlinePlus Topic]
- acute myeloid leukemia [SNOMED Notion]
- leukemia, myeloid, acute [MeSH Descriptor]
- leukemia, myeloid, acute [MeSH concept]
associated_with_malfunction_of_gene_product
- Annexin A8 [NCIt concept]
- Homeobox Protein Hox-A9 [NCIt concept]
- Interferon Regulatory Factor 1 [NCIt concept]
- Myosin-11 [NCIt concept]
- Nuclear Pore Complex Protein Nup98 [NCIt concept]
- Nuclear Pore Complex Protein Nup98-Nup96 [NCIt concept]
- Protein CBFA2T1 [NCIt concept]
- Protein DEK [NCIt concept]
- Receptor-Type Tyrosine-Protein Kinase FLT3 [NCIt concept]
concept_is_in_subset
- CPTAC Acute Myeloid Leukemia Follow-Up Form [NCIt concept]
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Follow-Up Forms Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Portfolio Management Subtype Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- CTS-API Disease Main Type Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Clinical Trials Search-Application Programming Interface Disease Category Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Adverse Events Terminology [NCIt concept]
- Pediatric Adverse Events Terminology Mapped to MedDRA [NCIt concept]
- Pediatric Hematology-Oncology Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloblast [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_accepted_treatment_with_regimen
- TAD Regimen [NCIt concept]
disease_has_associated_gene
- ABI1 Gene [NCIt concept]
- ABI1 wt Allele [NCIt concept]
- ABL2 Gene [NCIt concept]
- ABL2 wt Allele [NCIt concept]
- ARNT Gene [NCIt concept]
- ARNT wt Allele [NCIt concept]
- DCK Gene [NCIt concept]
- DCK wt Allele [NCIt concept]
- EPS15 Gene [NCIt concept]
- EPS15 wt Allele [NCIt concept]
- HOXA9 Gene [NCIt concept]
- HOXA9 wt Allele [NCIt concept]
- MIR29B1 Gene [NCIt concept]
- MIR29B1 wt Allele [NCIt concept]
- MIR29B2 Gene [NCIt concept]
- MIR29B2 wt Allele [NCIt concept]
- MIR320A Gene [NCIt concept]
- MIR320A wt Allele [NCIt concept]
- NPM1 Gene [NCIt concept]
- NPM1 wt Allele [NCIt concept]
- NUP98 Gene [NCIt concept]
- NUP98 wt Allele [NCIt concept]
- Oncogene ABL1 [NCIt concept]
- Oncogene KIT [NCIt concept]
- PURA Gene [NCIt concept]
- PURA wt Allele [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]

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