" /> Protein CBFA2T1 - CISMeF





Preferred Label : Protein CBFA2T1;

NCIt synonyms : Eight Twenty One Protein; Cyclin D Related Protein; Acute Myelogenous Leukemia 1 Translocation 1 Protein MTG8B; CBFA2T1; ETO; Acute Myelogenous Leukemia 1 Translocation 1 Protein MTG8A; Cyclin D-Related; Acute Myelogenous Leukemia 1 Translocation 1 Protein MTG8C; Core-Binding Factor, Alpha Subunit 2, Translocated to 1; MTG8 Protein; Zinc Finger MYND Domain Containing Protein 2; Cyclin-D-Related Protein; ETO Protein; Zinc Finger MYND Domain-Containing Protein 2; Protein ETO; Protein MTG8;

NCIt definition : Protein CBFA2T1 (604 aa, 68 kDa) is encoded by the human RUNX1T1 gene. This protein plays a role in the regulation of gene transcription.;

NCIt note : ETO Protein is a putative MYND zinc finger transcription factor expressed as multiple isoforms in brain, heart, lung, pituitary, skeletal muscle, pancreas, placenta, testis, and ovary. MTG8B and MTG8C variants have distinct N-termini. One frameshifted MTG8 variant lacks C-terminal zinc fingers, a P/S/T-rich domain, and a coiled-coil structure. Associated with NCOR/HDAC, this protein may repress transcription and differentiation in hematopoietic precursors. (from LocusLink, Swiss-Prot, OMIM);

Détails


Vous pouvez consulter :


Nous contacter.
29/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.