PURA wt Allele

Preferred Label : PURA wt Allele;

NCIt synonyms : Purine-Rich Element Binding Protein A wt Allele; PUR-Alpha; PUR1; PURALPHA; PURA;

NCIt definition : Human PURA wild-type allele is located within 5q31 and is approximately 3 kb in length. This allele, which encodes transcriptional activator protein Pur-alpha, is involved in both DNA replication and transcription. The deletion of this gene has been implicated in myelodysplastic syndrome and acute myelogenous leukemia.;

GenBank Accession Number : NM_005859;

Details

Origin ID

C51297;

UMLS CUI

C1706344;

False automatic mappings
- Pus [LOINC System]
- Pus (morphologic abnormality) [SNOMED CT concept]
- Pus (substance) [SNOMED CT concept]
- pus [MeSH concept]
- pus, nos [SNOMED Notion]
OMIM relation
- Purine-rich element-binding protein a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Acute Myeloid Leukemia [NCIt concept]
- Myelodysplastic Syndrome [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5q31 [NCIt concept]
gene_plays_role_in_process
- DNA Replication [NCIt concept]
- Replication-Associated Process [NCIt concept]
- Transcriptional Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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