ARNT wt Allele

Preferred Label : ARNT wt Allele;

NCIt synonyms : HIF1beta Gene; Dioxin Receptor, Nuclear Translocator Gene; HIF-1 Beta Gene; Hypoxia-Inducible Factor 1 Beta Gene; HIF1-Beta Gene; Aryl Hydrocarbon Receptor Nuclear Translocator wt Allele; HIF1B; HIF-1beta; Hypoxia-Inducible Factor 1, Beta Subunit Gene; ARNT; HIF-1Beta Gene; HIF1B Gene; HIF1BETA; TANGO; bHLHe2; HIF-1-beta;

NCIt definition : Human ARNT wild-type allele is located in the vicinity of 1q21 and is approximately 67 kb in length. This allele, which encodes aryl hydrocarbon receptor nuclear translocator protein, plays a role in the modulation of the transcriptional response to halogenated aromatic hydrocarbons. This gene and the ETV6 gene are involved in a translocation t(1;12)(q21;p13) that is associated with acute myeloblastic leukemia.;

GenBank Accession Number : NM_178427;

Details

Origin ID

C52509;

UMLS CUI

C1704839;

OMIM relation
- Aryl hydrocarbon receptor nuclear translocator [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Acute Myeloid Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 1: 147662259-147595259 [NCIt concept]
gene_in_chromosomal_location
- 1q21 [NCIt concept]
gene_is_element_in_pathway
- AHR Signal Transduction Pathway [NCIt concept]
- Angiogenesis Pathway [NCIt concept]
- Erythropoietin Neuroprotection Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- HIF-2-Alpha Transcription Factor Pathway [NCIt concept]
- Hypoxia and Oxygen Homeostasis Regulation of HIF-1-Alpha Pathway [NCIt concept]
- Hypoxia-Inducible Factor Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Ligand Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients