Oncogene KIT - CISMeF

Preferred Label : Oncogene KIT;

NCIt synonyms : PBT; KIT; Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog;

NCIt definition : Cloned cancer gene for Familial gastrointestinal stromal tumors (GIST), KIT proto-oncogene encodes a putative transmembrane receptor tyrosine kinase for stem cell factor and is critical in the development of pluripotent hematopoietic stem cells, migrating embryonic melanoblasts, and primordial germ cells. The human proto-oncogene is located at 4q12.;

NCI Metathesaurus CUI : CL433119;

GenBank Accession Number : X06182;

Details

Origin ID

C18348;

UMLS CUI

C1416655;

OMIM relation
- Kit protooncogene, receptor tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- KIT proto-oncogene, receptor tyrosine kinase [HGNC gene]
- Kit protooncogene, receptor tyrosine kinase [OMIM gene]
gene_associated_with_disease
- Acute Myeloid Leukemia [NCIt concept]
- Gastrointestinal Stromal Tumor [NCIt concept]
- Germ Cell Tumor [NCIt concept]
- Mast Cell Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 4q11-q12 [NCIt concept]
gene_plays_role_in_process
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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