Angiopoietin-2

Preferred Label : Angiopoietin-2;

NCIt synonyms : Angiopoietin 2; Ang-2; ANGPT2; Ang2; Tie2-Ligand;

NCIt definition : Angiopoietin-2 (496 aa, 57 kDa) is encoded by the human ANGPT2 gene. This protein plays a role in the regulation of endothelial cell apoptosis.;

Details

Origin ID

C18056;

UMLS CUI

C3849511;

Currated CISMeF NLP mapping
- Angiopoietin-2 [MeSH Descriptor]
- Angiopoietin-2 [MeSH concept]
OMIM relation
- Angiopoietin 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ANGPT2 protein, human [MeSH Supplementary Concept]
- ANGPT2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ANGPT2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
gene_product_is_element_in_pathway
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Angiopoietin-2-specific Fusion Protein PF-04856884 [NCIt concept]
- Anti-ANG2 Monoclonal Antibody MEDI-3617 [NCIt concept]
- Anti-VEGF/ANG2 Nanobody BI 836880 [NCIt concept]
- Anti-angiopoietin Monoclonal Antibody AMG 780 [NCIt concept]
- Faricimab [NCIt concept]
- Nesvacumab [NCIt concept]
- Trebananib [NCIt concept]
- Vanucizumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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