NCIt definition : A fully human monoclonal antibody directed against angiopoietin 2 (ANG2) with potential
antiangiogenic and antineoplastic activities. Nesvacumab binds to ANG2 and interferes
with the interaction between Ang2 and its receptor TEK tyrosine kinase (Tie2), which
may inhibit tumor cell angiogenesis and tumor cell proliferation. ANG2 is upregulated
in a variety of cancer cell types and plays a crucial role in angiogenesis.;
UNII : WX8293WGLC;
CAS number : 1296818-77-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1296818-77-3
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G-SRS /a ;
Semantic type(s)