Trebananib - CISMeF

Preferred Label : Trebananib;

NCIt synonyms : Angiopoietin 1/2-Neutralizing Peptibody AMG 386;

NCIt definition : An angiopoietin (Ang) 1 and 2 neutralizing peptibody, with potential antiangiogenic activity. AMG 386 targets and binds to Ang1 and Ang2, thereby preventing the interaction of the angiopoietins with their target tie2 receptors. This may inhibit angiogenesis and may eventually lead to an inhibition of tumor cell proliferation.;

UNII : X8Y5U6NC7E;

CAS number : 894356-79-7;

Molecule name : AMG 386; AMG-386;

Codes from synonyms : 513;

Details

Origin ID

C91711;

UMLS CUI

C3660912;

Automatic exact mappings (from CISMeF team)
- trebananib [MeSH concept]
- trebananib [MeSH Supplementary Concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- trebananib [MeSH concept]
- trebananib [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Angiopoietin-1 [NCIt concept]
- Angiopoietin-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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